Botox vs Fillers: what's the difference? Cosmopolitan Clinic Amsterdam


If celebrities suddenly look very different, you often hear that they have used (too much) botox. However, this is not always correct: botox and fillers are often confused. It is true that both can fight wrinkles and they are both injectables. Injectables is a collective name for botox, fillers, Profhilo, and other skin boosters. These are all injectable and provide a younger, fresher, and tighter look and/or shape. They all achieve a different effect, in this article, the difference between botox and fillers is explained.


Botox

Botox is actually a brand name, the active substance of which is botulinum toxin type A. Botulinum toxin is a neurotoxin, a natural protein that relaxes muscles. Because the active ingredient relaxes the muscles, this type of injectable is usually used to treat wrinkles caused by increased muscle tension. Consider, for example, fine lines that emerge through expression, such as when laughing, frowning, and looking surprised.


Relaxation of the muscle makes the skin smoother and tighter, causing wrinkles to look softer. For example, a wrinkle relaxer is often used to smoothen the frown lines, forehead lines, and crow’s feet. Botulinum toxin can also be used to counteract increased muscle tension, such as grinding teeth or clenching the jaw. In addition, the injectable can also be used against excessive sweating, as the effect also blocks the sweat glands. Moreover, botulinum toxin can be used for a gummy smile. The botulinum toxin effect is only temporary: approximately between three to five months.

At Cosmopolitan Clinic Amsterdam we work with the brand Bocouture, which is the purest neurotoxin on the market. Bocouture does not contain any unnecessary proteins, so there is a very low chance that an allergic reaction will occur. For more applications of wrinkle relaxers and fillers see the image below.


Fillers

(Dermal) Fillers are injectables that have a volumizing effect. Fillers are used for various purposes. For example, you can use fillers to add volume, such as to the lips. Fillers can also restore volume loss, such as with the tear troughs. Fillers can also help improve contours, such as the cheekbones, jawline, or through a liquid nose job.




Fillers can be used to soften and reduce wrinkles. Examples of this are the nasolabial folds, décolletage lines, and marionette lines. Unlike botox, the lines are literally filled in when using fillers, hence the name.

Most fillers are based on hyaluronic acid. Other fillers such as calcium hydroxylapatite or polylactic acid filler have an additional biostimulatory effect whereby the collagen production of the skin is stimulated. Nowadays fillers have a temporary effect and are biodegradable. Depending on the type of filler and the treatment location, fillers will last between six and twenty-four months.

So what is the difference between botox or fillers?

Botox and fillers achieve a completely different effect. Botox causes the muscles to relax, making the skin smoother. Botulinum toxin is therefore especially suitable for lines in places where the face moves by expression. In contrast, the effect of fillers is to add volume, so they quite literally fill up. The choice between botox and fillers is therefore completely dependent on the effect you want to achieve. Botox and fillers can also be used together, they can support each other. A good cosmetic doctor has an expert eye for this. He/she can advise you on this, so that you can obtain your desired look.


door drs. Leanne Wong 7 oktober 2025
Waarom de herfst hét moment is om te starten met peelings of huidverbetering  De zomer heeft ons huid vaak flink op de proef gesteld: zon, warmte, zeezout en airco kunnen leiden tot pigmentvlekjes, een doffe teint of vroegtijdige veroudering. Daarom is de herfst de ideale periode om te starten met peelings of huidverbeterende behandelingen . Waarom herfst? Minder zonblootstelling: in de herfst is de UV-index lager, waardoor je huid beter kan herstellen na een peeling. Herstel na de zomer: pigment en zonneschade kunnen direct worden aangepakt. Boost voor de winter: een peeling stimuleert collageen en maakt de huid sterker tegen koude en droge lucht. Welke behandelingen zijn ideaal? Chemische peelings: verminderen pigment, fijne lijntjes en geven een frisse glow. SkinPen Microneedling: stimuleert collageen en verbetert huidstructuur. Skinboosters (zoals Profhilo of Belotero Revive): hydrateren diep en herstellen balans. Thuisverzorging als aanvulling Combineer behandelingen altijd met goede producten. Denk aan een retinol (zoals de Retinol+ Emulsion 0.3 van iS Clinical) voor celvernieuwing, en uiteraard een dagelijkse SPF . 👉 Plan een intake bij onze huidspecialisten of artsen om samen te bepalen welke aanpak het beste past bij jouw huiddoelen. Why Autumn is the Best Time to Start Peels and Skin Rejuvenation Summer can take a toll on our skin: sun, heat, saltwater, and air conditioning often leave behind pigmentation spots, dullness, or early signs of aging. That’s why autumn is the ideal season to start peels or skin rejuvenation treatments . Why autumn? Less sun exposure: UV levels are lower, so your skin can safely recover after a peel. Post-summer repair: it’s the perfect moment to target pigmentation and sun damage. Boost before winter: peels stimulate collagen and prepare your skin to handle cold and dry air. Which treatments work best now? Chemical peels: reduce pigmentation, fine lines, and restore radiance. SkinPen Microneedling: stimulates collagen and improves skin texture. Skinboosters (like Profhilo or Belotero Revive): deeply hydrate and restore balance. Homecare for extra results Always combine your treatments with the right skincare. A retinol (such as iS Clinical’s award-winning Retinol+ Emulsion 0.3) supports cell turnover, while a daily SPF keeps your results protected. 👉 Book a consultation with our specialists or doctors to create a personalized plan that fits your skin goals.
door drs. Leanne Wong 6 augustus 2025
Stralend de zomer in: ontdek LED-lichttherapie met Dermalux Flex
door Leanne . 4 juli 2025
Wist je dat suiker niet alleen invloed heeft op je energie en gewicht, maar ook op hoe je huid eruitziet? Een proces genaamd glycosylatie (of "glycation" in het Engels) zorgt ervoor dat overtollige suikers zich binden aan collageen en elastine. Dit zijn twee belangrijke bouwstenen van een stevige en jonge huid. Het resultaat? Verslapping, rimpels en een doffe teint. In deze blog leggen we uit wat glycosylatie is, hoe je het kunt remmen via voeding én welke producten van iS Clinical je huid kunnen helpen herstellen en beschermen. Wat is glycosylatie precies? Glycosylatie is een natuurlijk proces waarbi j suikermoleculen zich binden aan eiwitten in je lichaam. Hierdoor ontstaan schadelijke verbindingen, ook wel AGE’s (Advanced Glycation End Products) genoemd. Deze AGE’s zorgen ervoor dat je huidstructuur stijver, brozer en minder elastisch wordt. Met andere woorden: je huid veroudert van binnenuit, vaak zonder dat je het doorhebt. Hoe herken je een ‘versuikerde’ huid? Rimpels en fijne lijntjes die dieper worden Verslapping van de huid, vooral rond kaaklijn en ogen Vale of gelige teint Minder elasticiteit en glans Wat kun je doen via voeding? Glycosylatie wordt versterkt door een hoge bloedsuikerspiegel. Gelukkig kun je veel doen met je voedingspatroon: Beperk snelle suikers –> zoals frisdrank, koekjes en wit brood Eet antioxidantenrijk –> zoals bessen, kurkuma, groene bladgroenten Kies vezels & eiwitten –> voor een stabiele bloedsuikerspiegel Drink voldoende water –> voor hydratatie en celvernieuwing De oplossing van iS Clinical bij huidveroudering door suiker Bij Cosmopolitan Clinic werken we met iS Clinical vanwege de hoge concentratie actieve ingrediënten en klinische effectiviteit. Deze producten helpen de huid te herstellen en beschermen tegen schade door glycosylatie. Aanbevolen iS Clinical producten: 1. Super Serum Advance+ Met gestabiliseerde vitamine C en kopertripeptiden ➡ Stimuleert collageen ➡ Vermindert schade door vrije radicalen 2. GenexC Serum Met 20% vitamine C en krachtige antioxidanten ➡ Helpt bij DNA-bescherming ➡ Verbetert elasticiteit en celvernieuwing 3. Reparative Moisture Emulsion Hydratatie + bescherming met Extremozymes® ➡ Herstelt huidbarrière ➡ Vertraagt zichtbare veroudering 4. Youth Intensive Crème Rijke anti-aging nachtcrème met hyaluronzuur en peptiden ➡ Verstevigt, hydrateert en verzacht ➡ Vermindert tekenen van glycosylatie Conclusie Een gezonde huid start van binnenuit. Door slimme voeding en effectieve huidverzorging kun je de gevolgen van glycosylatie aanzienlijk beperken. Onze huidexperts helpen je graag met persoonlijk advies over voeding én huidproducten. Kom langs bij Cosmopolitan Clinic Amsterdam of plan een huidconsult in! Samen brengen we jouw natuurlijke schoonheid naar voren! ENGLISH Sugar-Damaged Skin? Here’s How to Slow Down Aging from Within Did you know that sugar doesn’t just affect your energy or weight? It can als o accelerate how your skin ages? A biological process called glycation (or glycosylation) causes excess sugar to bind to collagen and elastin. The two proteins that keep your skin firm and youthful. The result? Sagging, wrinkles, and a dull complexion. In this blog, we explain what glycation is, how to reduce it through nutrition, and which iS Clinical pro ducts help support and protect your skin. What is glycation? Glycation is a natural process where sugar molecules attach to proteins in the body, forming harmful compounds called AGEs (Advanced Glycation End Products). These AGEs stiffen and weaken your collagen and elastin fibers, leading to skin that’s less elastic and more prone to wrinkles. Signs your skin is affected by glycation: Fine lines and deeper wrinkles Loss of firmness, especially around jawline and eyes A dull or yellowish complexion Reduced glow and elasticity What you can do through nutrition: Glycation is strongly influenced by high blood sugar levels. Here’s how to fight back from the inside: Limit refined sugars –> like soda, sweets, white bread Eat antioxidant-rich foods –> such as berries, turmeric, green veggies Go for fiber and protein –> to keep blood sugar stable Drink plenty of water –> to hydrate and support cell renewal How iS Clinical helps your skin recover At Cosmopolitan Clinic, we love working with iS Clinical because of their clinically proven active ingredients. Their formulas help repair and protect the skin from glycation-related damage. Recommended iS Clinical products: 1. Super Serum Advance+ Contains stabilized Vitamin C and copper tripeptides ➡ Stimulates collagen production ➡ Protects against free radical damage 2. GenexC Serum Packed with 20% Vitamin C and powerful antioxidants ➡ Helps protect cellular DNA ➡ Supports skin elasticity and renewal 3. Reparative Moisture Emulsion Hydrating + barrier-repair formula with Extremozymes® ➡ Strengthens skin barrier ➡ Slows down visible aging 4. Youth Intensive Crème Luxurious night cream with hyaluronic acid and peptides ➡ Deeply hydrates and firms ➡ Reduces signs of sugar-induced aging Final Thoughts Healthy skin starts from within. By combining smart nutrition with targeted skincare, you can significantly reduce the impact of glycation. Want personal advice? Our experts at Cosmopolitan Clinic Amsterdam are happy to help you bring out your natural beauty! Glowing from the inside out!
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