What is a biostimulator? Explanation of Lanluma and Radiesse
Loss of firmness, sagging skin, or subtle volume loss in the face or body often develops gradually. Not everyone wants to immediately add extra volume with fillers. Therefore, biostimulators are increasingly being chosen. But what exactly is a biostimulator, and what can you realistically expect from treatments such as Lanluma and Radiesse? In this blog, we explain clearly and with medical backing how these treatments work and for whom they are suitable.
Table of contents
- What is a biostimulator
- How does collagen stimulation work
- Difference between a filler and a biostimulator
- Explanation about Lanluma
- Explanation about Radiesse
- When do you choose a biostimulator?
- Results and expectations
- Costs and treatment process
- Frequently Asked Questions
- Facts and sources
What is a biostimulator?
A biostimulator is an injectable treatment that stimulates the body to produce collagen itself. Instead of directly adding volume, the product activates a natural process in the skin.
Collagen is a structural protein that provides firmness, elasticity, and support to the skin. From approximately the age of 25, collagen production gradually declines. This can lead to:
A biostimulator focuses on improving skin structure from within.

How does collagen stimulation work?
After injection, the product is gradually broken down by the body. During this process, the production of new collagen is stimulated.
This means:
The effect is therefore less immediately visible than with fillers.
Difference between a filler and a biostimulator
The difference is important to understand.
Fillers:
Biostimulatoren:
Sometimes both techniques are combined, depending on the treatment plan.
What is Lanluma?
Lanluma is a biostimulator based on poly-L-lactic acid (PLLA). This substance has been safely used in medicine for many years.
Lanluma:
Multiple sessions are usually required for optimal results.
What is Radiesse?
Radiesse contains calcium hydroxylapatite (CaHA), a substance that occurs naturally in the body.
Radiesse:
Radiesse thus combines direct structure with biostimulation.
When should you choose a biostimulator?
A biostimulator may be suitable for:
Not everyone is automatically suitable. During a consultation, we assess skin condition, expectations, and medical history.
Results and realistic expectations
Important to know:
A biostimulator is not a quick fix, but a gradual improvement.
Frequently Asked Questions
Does a biostimulator hurt?
The treatment is performed under anesthesia where necessary. The discomfort is generally well tolerated.
Do I see immediate results?
With Radiesse, slight immediate support may be visible. The real effect develops gradually.
Is it safe?
When administered by an experienced physician and with the correct indication, these products are considered safe.
How many treatments are needed?
Often, 2 to 3 sessions are needed, depending on the goal.
Can it be combined with fillers?
Yes, in some treatment plans, techniques are combined for a balanced result.
Citation
| Claim | Source |
|---|---|
| Collagen decline from age 25 | Shuster et al., Br J Dermatol |
| Calcium hydroxylapatite applications | Journal of Cosmetic Dermatology |
| Poly-L-lactic acid safety | Aesthetic Surgery Journal |
| Biostimulation and skin firming | Dermatologic Surgery Journal |
Personal advice
A biostimulator such as Lanluma or Radiesse stimulates the body to produce collagen itself. The results develop gradually and focus on skin improvement and firming from within. During a personal consultation, we carefully assess whether this treatment is suitable for your skin condition and wishes.






